St. Michaels is a small town.  According to the 2010 United States Census, St. Michaels has a population of 1020 full-time residents in town.  The greater St. Michaels area in unincorporated parts of Talbot County (with the zip code 21663) is home to 3308 people.

St. Michaels is an educated town.  Of those residents 25 years of age and older, 95% have a high school diploma, 35% have a college degree, and 15% have graduate degrees.  Residents work locally in many professional capacities and work from home for national companies in sales and other jobs.  There are many jobs in retail, construction, and accommodation and food service due to tourism.

St. Michaels is a town for people in all stages of life, from starting a family to retiring.  The town is home to slightly more females than males, and the approximate median age of residents is 50 years old.  More than half of the households are families with an average family size of 2.67.  Approximately three-quarters of the population are white, and more than one-quarter of the population is African-American.

St. Michaels is a safe town. Violent crime is virtually non-existent.  In a town where most everyone knows your name or at least recognizes your face, neighbors watch out for neighbors, parents look out for children, and community safety is paramount.